Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ GPR55 Receptor Antagonist, CID16020046
A selective antagonist of G protein-coupled receptor 55 (GPR55) that blocks lipid L-a-lysophosphatidylinositol (LPI, Cat
MilliporeSigma™ Calbiochem™ Aloisine A
A cell-permeable pyrrolo-pyrazine compound that exerts anti-proliferative effects.
MilliporeSigma™ Calbiochem™ V-ATPase Inhibitor, KM91104
A cell-permeable, non-macrolide small molecule V-ATPase inhibitor that specifically targets the a3-b2 subunit protein protein interation of V-ATPase (IC50 o
MilliporeSigma™ Calbiochem™ I-BET
A cell-permeable benzodiazepine compound that binds the tandem bromodomains of BET (bromodomain and extra terminal domain) family members BRD2 (1-473), BRD3 (1-434), and BRD4 (1-477) with high affinity.
MilliporeSigma™ Calbiochem™ Colchicine, Colchicum autumnale
Colchicine, Colchicum autumnale, CAS 64-86-8, is an inhibitor of mitosis that disrupts microtubules and inhibits tubulin polymerization. Induces apoptosis in PC12 and cerebellar granule cells.
MilliporeSigma™ Calbiochem™ Meloxicam
A cell-permeable, non-steroidal anti-inflammatory drug (NSAID) of the oxicam family which preferentially inhibits the inducible isoform of COX-2 (IC50 = 4.7 μM) relative to COX-1 (IC50 = 36.6 μM).
MilliporeSigma™ Calbiochem™ GM 6001
GM 6001, CAS 142880-36-2, is a potent, cell-permeable, broad-spectrum inhibitor of matrix metalloproteinases.
MilliporeSigma™ Calbiochem™ TLR8 Agonist, cpd14b
A potent agonist of Toll-like receptor 8 agonist (TLR8, EC50 = 200 nM).
MilliporeSigma™ Calbiochem™ InSolution™ Casein Kinase II Inhibitor I
The InSolution™ Casein Kinase II Inhibitor I controls the biological activity of Casein Kinase II. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ (--)-Nicotine, Ditartrate
Potent agonist of the nicotinic acetylcholine receptor.
MilliporeSigma™ Calbiochem™ InSolution™ Lovastatin, Sodium Salt
Carboxylate form of Lovastatin that is active in whole cells and cell-free assays.
MilliporeSigma™ Calbiochem™ Rho Kinase Inhibitor
The Rho kinase inhibitor, CAS 872543-07-6, is a cell-permeable, highly specific, reversible, potent, and ATP-competitive inhibitor of Rho-associated kinase (ROCK; Ki = 1.6 nM).
MilliporeSigma™ Calbiochem™ PKM2 Activator II, DASA
The PKM2 Activator II, DASA modulates the biological activity of PKM2. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ InSolution™ OM99-2
An eight residue peptidomimetic, tight binding transition-state analog inhibitor of human brain memapsin 2.
MilliporeSigma™ Calbiochem™ Granzyme B Inhibitor I
The Granzyme B Inhibitor I controls the biological activity of Granzyme B. This small molecule/inhibitor is primarily used for Cancer applications.